Dou Lab at Clemson University
We study how protozoan pathogens survive, invade hosts, and transmit disease.
The Dou Lab uses molecular biology, cell biology, biochemistry, infection models, and drug discovery approaches to understand the pathogenesis of Toxoplasma gondii and Histomonas meleagridis.
Recruiting Ph.D. Students and Postdoctoral Fellows
We welcome motivated scientists interested in parasite biology, host-pathogen interactions, molecular microbiology, cell biology, biochemistry, and animal health. Prospective graduate students and postdoctoral fellows are encouraged to contact Dr. Zhicheng Dou with a CV and a brief description of research interests.
Research Themes
Digestive Vacuole Biology
We investigate how lysosome-like organelles in Toxoplasma gondii support parasite survival, replication, invasion, egress, and dissemination.
Heme Metabolism
We study how heme-related pathways shape intracellular parasite survival, stress responses, and pathogenesis.
Transmission and Virulence
We examine molecular mechanisms that contribute to Histomonas meleagridis infection and transmission in poultry.
Training in a Collaborative Lab
Our lab brings together postdoctoral fellows, graduate students, staff, and undergraduate researchers who share an interest in rigorous science and supportive mentorship.
Trainees gain experience in experimental design, molecular and cellular methods, scientific communication, manuscript preparation, and collaborative problem solving.
Recent Highlights
- Recent publications in mSphere, mBio, Nature Communications, ACS Infectious Diseases, and PLOS Pathogens.
- Ten years of the Dou Lab at Clemson University.
- Lab members present at regional and national microbiology and parasitology meetings.
- Undergraduate and graduate trainees have earned awards, fellowships, and placements in advanced training programs.
Molecular Biology of Protozoan Animal Pathogens in the Dou Lab at Clemson University 