Publications

  1. Key, M., Baptista CG., Bergmann A., Floyd, K., Blader, IJ., Dou, Z.*, 2024, “Toxoplasma gondii harbors a hypoxia-responsive coproporphyrinogen dehydrogenase-like protein.” mSphere, e0009224 (*, corresponding author)
  2. Carruthers, V.B., Dou, Z.*, 2024, “Deciphering protein prenylation in endocytic trafficking in Toxoplasma gondii.” mBio, e0028324 (*, corresponding author)
  3. Aghabi, D., Sloan, m., Gill, G., Hartmann, E., Antipova, O., Dou, Z., Guerra, AJ., Carruthers, VB., Harding, CR., 2023, ” The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii.” Nature Communications, 14(1): 3659.
  4. Thornton, LB., Key, M., Micchelli, C., Stasic, AJ., Kwain, S., Floyd, K., Moreno, SNJ., Domiony, BN., Whitehead, DC., Dou, Z.*, 2023, “A cathepsin C-like protease mediates the post-translation modification of Toxoplasma gondiisecretory proteins for optimal invasion and egress.” mBio, e0017423 (*, corresponding author)
  5. Malave-Ramos, DR., Kennedy, K., Key, MN., Dou, Z., Kafsack, BFC., 2022, “Safe, Effective, and Inexpensive Clearance of Mycoplasma Contamination from Cultures of Apicomplexan Parasites with Sparfloxacin.” Microbiol Spectr, 10(5):e0349722.
  6. Stasic, AJ., Moreno, SNJ., Carruthers, VB., Dou, Z., 2022, “The Toxoplasma plant-like vacuolar compartment (PLVAC).” J Eukaryot Microbiol, 69(6): e12951.
  7. Rees, K.C.#, Dou, Z.#,*, Whitehead, D.C*., 2022, “Oxadiazon Derivatives Elicit Potent Intracellular Growth Inhibition against Toxoplasma gondii by Disrupting Heme Biosynthesis.” ACS Infectious Diseases, 8(5):911-917. (#, first author; *, corresponding author; Featured research article)
  8. Piro, F., Focaia, R., Dou, Z., Masci, S., Smith, D., Di Cristina, M., 2021, “An Uninvited Seat at the Dinner Table: How Apicomplexan Parasites Scavenge Nutrients from the Host.” Microorganisms, 9(12): 2592
  9. Bergmann, A., Dou, Z*. 2021, “Fluorescence-based Heme Quantification in Toxoplasma gondii.” Bio-protocol, 11(12): e4063 (*, corresponding author)
  10. Bergmann, A., Floyd, K., Key, M., Dameron, C., Rees, K.C., Thornton, L.B., Whitehead, C.D., Hamza, I., Dou, Z*., 2020, “Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection.” PLOS Pathogens, 16(5): e1008499. (*, corresponding author)
  11. McDonald, C.#, Smith, D.#, Di Cristina, M., Kannan, G., Dou, Z.#,* Carruthers, V. B.*, 2020, “Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 are dispensable for endolysosomal protein digestion.” mSphere, 5(1): e00869-19 (#, first author; *, corresponding author.) (IF = 4.447)
  12. Key, M., Bergmann, A., Micchelli, C., Thornton, L.B., Millard, S., Dou, Z.*, 2020, “Determination of Chemical Inhibitor Efficiency against Intracellular Toxoplasma gondiiGrowth Using a Luciferase-Based Growth Assay.” Journal of Visualized Experiments, (158), e60985. (*, corresponding author.)
  13. Thornton, L.B., Teehan, P., Floyd, K., Cochrane, C., Bergmann, A., Riegel, B., Stasic, A.J., Di Cristina, M., Moreno, S.N.J., Dou, Z*., 2019, “An ortholog of falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion.” PLOS Pathogens, 15(6):e1007775. (Featured research article; *, correspondence author).
  14. Di Cristina, M., Dou, Z., Lunghi, M., Kannan, G., Huynh, M.H., McGovern, O., Schultz, T., Schultz, A., Miller, A., Hayes, B., van der Linden, W., Emiliani, C., Bogyo, M., Besteiro, S., Coppens, I., Carruthers, V.B., 2017, “Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection.” Nature Microbiology, 2, 17096
  15. Cai, F., Dou, Z., Bernstein, S.L., Leverenz, R., Williams, E.B., Heinhorst, S., Shively, J.M., Cannon, G.C., and Kerfeld, C.A., 2014, “Advances in understanding carboxysome assembly in Prochlorococcus and Synechococcusimplicate CsoS2 as a critical component.” Life, 5(2): 1141-71 (IF = 3.24)
  16. Dou, Z., McGovern, O., Di Cristina, M., and Carruthers, V.B., 2014, “Toxoplasma gondii ingests and digests host cytosolic proteins.” mBio, 5(4): e01188-14 (Highlighted by a spotlight article in Trends in Parasitology)
  17. Warring, S., Dou, Z., Carruthers, V.B., McFadden, G., and van Dooren, G., 2014, “Characterization of the Chloroquine Resistance Transporter homologue in Toxoplasma gondii.” Eukaryotic Cell, 13(11): 1360-70 (cover article)
  18. Liu, J., Pace, D., Dou, Z., Guidot, D., Carruthers, V.B., and Moreno, N.J., 2014, “A Vacuolar-H+-Pyrophosphatase (TgVP1) is Required for Microneme Secretion, Host Cell Invasion, and Extracellular Survival of Toxoplasma gondii.” Mol Microbiol, 93(4):698-712
  19. Dou, Z., Coppens, I., and Carruthers, V.B., 2013, “Non-canonical maturation of two papain-family proteases in Toxoplasma gondii.” J Biol Chem, 288:3523-34, (cover article)
  20. Dou, Z., Carruthers, V.B., 2013, “TgCPL peptidase.” For Handbook of Proteolytic Enzymes, Third Edition. Elsevier Academic Press
  21. Saouros, S.#, Dou, Z.#, Henry, M., Simpson, P., Carruthers, V.B., and Matthews, S., 2012, “Inhibition of SUB1 from Toxoplasma gondii by MIC5 via a mechanism similar to subtilisin prodomains.” J Biol Chem, 287:36029-40, (#, co-first authors)
  22. Dou, and Carruthers, V.B., 2011, “Cathepsin proteases in Toxoplasma gondii”, Cysteine Proteases of Pathogenic Organisms.” Adv Exp Med Biol, 712:49-61.
  23. Iancu, C.V., Morris, D.M., Dou, Z., Heinhorst, S., Cannon, G.C., and Jensen, G.J., 2010, “Organization, structure, and assembly of α-carboxysomes determined by electron cryotomography of intact cells.” J Mol Biol, 396:105-17
  24. Menon, B.B., Dou, Z., Heinhorst, S., Shively, J.M., and Cannon, G.C., 2008, “Halothiobacillus neapolitanuscarboxysomes sequester heterologous and chimeric RubisCO species.” PLoS One, 3, e3570
  25. Dou, Z., Heinhorst, S., Williams, E.B., Murin, C.D., Shively, J.M. and Cannon, G.C., 2008, “CO2 Fixation kinetics of Halothiobacillus neapolitanus mutant carboxysomes lacking carbonic anhydrase suggest the shell acts as a diffusion barrier for CO2.” J Biol Chem, 283:10377-84